We deliver precision medicine through an innovative learning Mental health system that leverages clinical research and cutting-edge technology. Please see below for a glossary of selected terminology and our framework to deliver precision medicine.
Our Learning Mental Health System (LMHS) proposes a multi-level collaboration among a set of patients, providers, researchers, and health policymakers within a coordinated and integrated data flow to improve care and deliver individualized treatment for each patient. The data acquisition is initiated through multiple patient-clinician interactions providing longitudinal biopsychosocial data to the main clinical research data frame. Patient data is gathered by advanced technology, which is processed in an integrated data inter-frame through multiple encounters by a research team. An evidence repository will provide a continuous flow of information in real-time to optimize decision-making on all levels of the LMHS.
Singula Institute delivers Precision Medicine via a Learning Mental Health System that is focused on developing evidence-based and data-driven individualized mental health treatments for Anxiety and Depression.
Cognition– the mental action or process of acquiring knowledge and understanding through thought, experience, and sensory input
Emotion– a physiological brain response that corresponds to sensations of pleasure (i.e. positive valence emotions) or pain (i.e. negative valence emotions)
Emotional Processing– a series of cognitive functions that includes registration, identification, contextual understanding, leading to a decrease in the intensity of the experienced emotion
Attention- the ability to selectively choose relevant sensory stimuli while disregarding irrelevant sensory stimuli
Motivation– what initiates, guides, directs, and maintains goal-directed behavior
Memory– the ability to encode, store, recall, and retrieve information
Knowledge acquisition– the ability to memorize discrete factual information
Working memory– the ability to temporarily memorize information in order to internally manipulate, organize, and prioritize that information
Executive functioning– a set of mental skills that include working memory, flexible thinking, and self-control (or impulse control)
Impulse control– the ability to use cognitive processes such as judgment, logical reasoning, and problem solving prior to acting on a desired behavior
Judgment and evaluation– the ability to form values and preferences that are used to inform a decision-making process
Logical Reasoning– the ability to make inferences and draw conclusions based on knowledge as well as an evaluation of relationships between different aspects of a situation
Problem Solving– the ability to identify a deficiency, discrepancy, or error and use logical reasoning to form a plan or strategy to correct the deficiency, discrepancy, or error
Decision Making– the process of identifying and choosing alternatives based on one’s own values, preferences and beliefs
Behavior– A motor (muscle) response
Simple Behavior– A direct motor response to a sensory stimulus
Complex Behavior– A motor response through a set of decision making processes made possible through cognition and emotional processing
Affect– Behavioral expression of emotion
Emotional Valence– Positive (pleasurable) or negative (noxious) emotion
Positive (valence) Affect– Behavioral expressions of positive emotion
Negative (valence) Affect– Behavioral expressions of negative emotion
Reward– A physiological response to a stimulus, producing a pleasurable sensation
Punishment– A physiological response to a stimulus, producing a painful sensation; or a behavioral act whose intention is to induce negative emotion
Emotion Regulation– The ability to adjust, control, and dampen the intensity of an emotion in order to adapt to a situation.